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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/109648
Organ-on-a-chip microfluidic devices mimicking human splenic functions
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[spa] El progreso en el área de la microfluídica y en las metodologías de cultivo celular in vitro está posibilitando el desarrollo de sofisticados dispositivos que tienen como finalidad tratar de imitar algunas de las funciones fisiológicas de la unidad estructural y funcional mínima de un órgano. Esta nueva clase de dispositivos microfluídicos se denominan dispositivos "Órgano-en-un-Chip". El desarrollo de un modelo microfluídico del splenon-on-a-chip será el objetivo del estudio. Diferentes prototipos microfluídicos que pueden mimetizar, en la medida de lo posible, algunas de las propiedades del splenon, han sido diseñados.
[eng] Progress in the microfluidic technology and in the in vitro cell culture methodologies is making possible to microengineer sophisticated devices, trying to mimic some physiological functions of the minimal structural and functional subunit of an organ. This new class of microfluidic devices are called “Organ-on-a-Chip” devices. The development of a microengineered model of a splenon-on-a-chip will be the focus of this study. In this work, different microfluidic devices that could mimic, to the extent possible, some splenon properties, have been designed.
[eng] Progress in the microfluidic technology and in the in vitro cell culture methodologies is making possible to microengineer sophisticated devices, trying to mimic some physiological functions of the minimal structural and functional subunit of an organ. This new class of microfluidic devices are called “Organ-on-a-Chip” devices. The development of a microengineered model of a splenon-on-a-chip will be the focus of this study. In this work, different microfluidic devices that could mimic, to the extent possible, some splenon properties, have been designed.
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RIGAT BRUGAROLAS, Luis Guillermo. Organ-on-a-chip microfluidic devices mimicking human splenic functions. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/109648