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Treball de fi de grau

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cc-by-nc-nd (c) Sanz, 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/175895

Theoretical study of the relative stability of pyrrolidine enamines and their nitro derivatives in α, β, γ and δ positions

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The chemistry of enamines has gained importance in recent years due to the increased popularity of asymmetric organocatalysis using chiral secondary amines. The main goal of this dissertation is to gain insight, from a theoretical point of view, of the position of the equilibrium involved in the catalytic cycle of nitro-Michael reactions between the product enamine, containing a nitro group, and the starting aldehyde enamine.To do so, the energies of the species involved in the equilibria shown below were calculated, at different levels of theory. The calculations were performed with the Gaussian computational chemistry package and some scripts in Bash command language and in Python programming language were written to assist in the automatization of the process

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Treballs Finals de Grau de Química, Facultat de Química, Universitat de Barcelona, Any: 2020, Tutors: Anna Maria Costa Arnau, Jaume Vilarrasa i Llorens

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SANZ BERMAN, Pol. Theoretical study of the relative stability of pyrrolidine enamines and their nitro derivatives in α, β, γ and δ positions. [consulta: 24 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/175895]

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