Pharmacogenetics of ugt genes in North African populations

Vista senzilla d'ítem
dc.contributor.authorGaibar, M.
dc.contributor.authorNovillo, A.
dc.contributor.authorRomero-Lorca, A.
dc.contributor.authorEsteban i Torné, Maria Esther
dc.contributor.authorFernández-Santander, A.
dc.date.accessioned2019-05-21T11:44:54Z
dc.date.available2019-05-21T11:44:54Z
dc.date.issued2018-07-31
dc.date.updated2019-05-21T11:44:54Z
dc.description.abstractCytochrome P450 (CYP450), sulfotransferase (SULT), and glucuronidase (UGT) enzymes play roles in the phase I and phase II metabolism of most clinically prescribed drugs. As polymorphisms in these genes may alter enzyme activities, most prescribed drugs will differ in their efficacy and side effects. In prior work, we showed that besides polymorphisms in CYP450, those in SULT and UGT also give rise to different serum levels of some drug metabolites than detected in wild-type carriers of the genes [1]. [...]
dc.format.extent4 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec682037
dc.identifier.issn1470-269X
dc.identifier.urihttps://hdl.handle.net/2445/133582
dc.language.isoeng
dc.publisherSpringer Nature
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1038/s41397-018-0034-4
dc.relation.ispartofThe Pharmacogenomics Journal, 2018, vol. 18, p. 609-612
dc.relation.urihttps://doi.org/10.1038/s41397-018-0034-4
dc.rightscc by (c) Gaibar, M. et al., 2018
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)
dc.subject.classificationEnzims
dc.subject.classificationÀfrica del Nord
dc.subject.classificationFarmacogenètica
dc.subject.otherEnzymes
dc.subject.otherNorth Africa
dc.subject.otherPharmacogenetics
dc.titlePharmacogenetics of ugt genes in North African populations
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
682037.pdf
Mida:
275.51 KB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)
Articles publicats en revistes (Institut de Recerca de la Biodiversitat (IRBio))