Document type
ArticleVersion
Accepted versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/181547
Discussion of 'Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion' (Alvarez-Gonzalez, B.; Bastounis, E.; Meili, R.; del Alamo, J. C.; Firtel, R. A.; Lasheras, J. C.; 2014, Applied Mechanichs Reviews, 66(5), p. 050804)
Journal Title
Authors
Director/Tutor
Additional contribution
Journal ISSN
Volume Title
Abstract
A virtually universal feature of adherent cells is their ability to exert traction forces. To measure these forces, several methods have been developed over the past 15 years. In this issue of Applied Mechanics Reviews, Álvarez-González and co-workers review their own traction force microscopy approach and its application to the study of amoeboid cell locomotion. They show that the cycle of cell motility is exquisitely synchronized by a cycle of traction forces. In addition, they show how traction forces and cell cycle synchronization are affected by myosin and SCAR/WAVE mutants. Here, I discuss some open questions that derive from the work of the authors and other laboratories as regards the relationship between cell motility and traction forces.
Related resource
Subject (English)
Citation
Citation
TREPAT GUIXER, Xavier. Discussion of 'Cytoskeletal Mechanics Regulating Amoeboid Cell Locomotion' (Alvarez-Gonzalez, B.; Bastounis, E.; Meili, R.; del Alamo, J. C.; Firtel, R. A.; Lasheras, J. C.; 2014, Applied Mechanichs Reviews, 66(5), p. 050804). Applied Mechanics Reviews. 2014. Vol. 66, num. 5. ISSN 0003-6900. [consulted: 17 of October of 2026]. Available at: https://hdl.handle.net/2445/181547