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cc-by-nc-nd (c) Elsevier B.V., 2017
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/169453

Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture

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Recently it has been demonstrated that catanionic mixtures of oppositely charged surfactants have improved physicochemical-biological properties compared to the individual components. Isotherms of mixtures of an anionic biosurfactant (lichenysin) and a cationic aminoacid surfactant (C-3(LA)(2)) indicate a strong interaction suggesting the formation of a new 'pseudo-surfactant'. The antimicrobial properties of the mixture lichenysin and C-3(LA)(2) M80:20, indicate a synergistic effect of the components. The mechanism of action on the bacterial envelope was assessed by flow cytometry and Transmission Electron Microscopy. (C) 2016 Elsevier B.V. All rights reserved. Keywords: Antimicrobial properties; Arginine; Escherichia coli; Flow cytometry; Gemini surfactants; Lichenysin; Listeria nonocytogenes; Potassium leakage; Transmission electron microscopy.

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CORONEL LEÓN, Jonathan, et al. Lichenysin-geminal amino acid-based surfactants: Synergistic action of an unconventional antimicrobial mixture. Colloids and Surfaces B-Biointerfaces. 2017. Vol. 149, num. 38-47. ISSN 0927-7765. [consulted: 17 of June of 2026]. Available at: https://hdl.handle.net/2445/169453

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