Cellular senescence enhances adaptive anticancer immunosurveillance

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dc.contributor.authorMarin, Ines
dc.contributor.authorSerrano Marugán, Manuel
dc.contributor.authorPietrocola, Federico
dc.date.accessioned2023-01-10T11:55:18Z
dc.date.available2023-01-10T11:55:18Z
dc.date.issued2022-12-15
dc.date.updated2023-01-09T12:33:44Z
dc.description.abstractCancer therapy often induces senescence in some cancer cells. Senescent cells, due to their profoundly altered biology, may conceivably interact with the adaptive immune system in novel ways that may boost cancer immunosurveillance, triggering the clearance of both senescent and non-senescent neoplastic cells. In this regard, we have recently reported that senescent cancer cells exhibit potent antigenicity and adjuvanticity and can elicit strong CD8(+) T cell-dependent anticancer effects when used as vaccination agents.
dc.format.extent3 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idimarina6572486
dc.identifier.issn2162-402X
dc.identifier.pmid36531690
dc.identifier.urihttps://hdl.handle.net/2445/192013
dc.language.isoeng
dc.publisherTaylor & Francis
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1080/2162402X.2022.2154115
dc.relation.ispartofOncoImmunology, 2023, vol. 12, num. 1, p. 2154115
dc.relation.urihttps://doi.org/10.1080/2162402X.2022.2154115
dc.rightscc by-nc (c) Marin, Ines et al., 2022
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc/3.0/es/*
dc.sourceArticles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))
dc.subject.classificationEnvelliment
dc.subject.classificationInflamació
dc.subject.classificationInterferó
dc.subject.classificationVacunació
dc.subject.otherAging
dc.subject.otherInflammation
dc.subject.otherInterferon
dc.subject.otherVaccination
dc.titleCellular senescence enhances adaptive anticancer immunosurveillance
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))