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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/222467
Study of immune cells’ migration patterns in cancer
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Immune cells’ migration is a very important mechanism to respond to external infections or pathological process such as cancer. Although it is proved that cell migration in 3D spaces follow an anisotropic persistent random walk pattern (APRW), we prove in this work that this is not true for immune cells migrating in colorectal cancer (APC−/−) conditioned media. We develop a segmentation model for 3D images in order to track the cells. With the trackings, we demonstrate that in this media immune cells migrate at higher velocity and with straighter paths, contrary to what is described by APRW model.
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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2025, Tutor: Jordi Comelles Pujadas
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CANALETA VICENTE, Pau. Study of immune cells’ migration patterns in cancer. [consulted: 10 of June of 2026]. Available at: https://hdl.handle.net/2445/222467