Document type
Bachelor thesisPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/59751
Statistical Mechanics on the Regulation of Gene Expression
Journal Title
Authors
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
In recent years it has been shown that genetic information can be inherited through
the transcriptional state of the DNA, which can be either active or silenced. This is controlled by
chemical reactions of acetylation, which allows transcription, and methylation, which blocks it. We
have reproduced a computational model for this description and found that, in the thermodynamic
limit, a phase transition between the active and the silenced state should take place. Due to the lack
of physical frameworks to this problem, in this article we propose (up to our knowledge) the rst
statistical mechanics description based on an Ising model. We identify which is the critical temper-
ature of our system at which the phase transition occurs and discuss it in relation to experimental
data.
Description
Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Any: 2014, Tutora: Marta Ibañes
Subject (English)
Citation
Collections
Citation
MARTÍN VALDERRAMA, Víctor. Statistical Mechanics on the Regulation of Gene Expression. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/59751