Carregant...
Tipus de document
Treball de fi de grauData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/171468
Folding energy and kinetics of mutually interacting DNA Hairpins
Títol de la revista
Autors
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
The Szilard engine is a Maxwell demon thought experiment where information is converted into work. We propose a novel DNA molecule with two hairpins in serial that could act as a complex four-state Szilard engine using optical tweezers to apply a force. We synthesized the molecule with identical hairpins to perform two different experiments with optical tweezers, passive mode and pulling. Only 3 different states were observed as the intermediate state is degenerated. Their energy levels were obtained from kinetic rates measured in passive mode and work measured in pulling cycles. We conclude that the molecule follows well the
uctuation theorems and the Bell-Evans theory, with the exception of a Chevron type curvature in the kinetic rates due to the degeneration. The obtained data will help in the development and study of a Szilard engine with this molecule.
Descripció
Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2020, Tutors: Marc Rico, Fèlix Ritort
Matèries
Matèries (anglès)
Citació
Col·leccions
Citació
SCHÖNENBERGER SOLA, David. Folding energy and kinetics of mutually interacting DNA Hairpins. [consulta: 8 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/171468]