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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/174767
Effectiveness and Efficiency of Drug Eluting Stents
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Abstract
Coronary artery disease (CAD), also known as ischemic heart disease (IHD) and coronary
heart disease (CHD), is caused by the narrowing (stenosis) of one or more coronary arteries,
due to atherosclerosis, restricting blood flow and reducing the supply of oxygen to the heart
muscle. Transient shortages in blood flow and oxygen lead to angina pectoris and chest
pain, which may radiate to the left shoulder, arms, neck, back or jaw. Stable angina
symptoms do not tend to progress in intensity over time. More seriously, the rupturing of
an atherosclerotic plaque (causing a thrombotic occlusion) and stenosis of the vessel can
result in acute myocardial infarction (AMI) due to a critical reduction in the blood supply to
the heart muscle (myocardial ischemia). High levels of morbidity and mortality associated
with this infarction are a consequence of ischemia. It is vital to promptly re-establish
coronary blood flow after an infarction, because sustained ischemic damages and injuries to
the heart muscle may lead to sudden death or heart failure. In addition to infarction, acute
symptomatic manifestations of ischemic heart disease include unstable angina, and less
common conditions such as cardiogenic shock and sudden death (Thygesen, 2007)...
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MOREU, José, et al. Effectiveness and Efficiency of Drug Eluting Stents. Chapter 10 in: Gaze. David C. 2012. Coronary Artery Disease: Current Concepts in Epidemiology. Vol. Pathophysiology, num. IntechOpen. [consulted: 8 of June of 2026]. Available at: https://hdl.handle.net/2445/174767