A gram-scale route to phlegmarine alkaloids: rapid total synthesis of (-)-cermizine B
| dc.contributor.author | Bradshaw, Ben | |
| dc.contributor.author | Luque Corredera, Carlos | |
| dc.contributor.author | Bonjoch i Sesé, Josep | |
| dc.date.accessioned | 2026-01-09T09:56:49Z | |
| dc.date.available | 2026-01-09T09:56:49Z | |
| dc.date.issued | 2014-04-03 | |
| dc.date.updated | 2026-01-09T09:56:50Z | |
| dc.description.abstract | The synthesis of the Lycopodium alkaloid ( )-cermizine B (1), which establishes its absolute configuration, is achieved by combining asymmetric organocatalysis and an uninterrupted eight-step reaction sequence, followed by a final reduction step. This ''pot-economy'' strategy provides access to the cis-phlegmarine stereo parent embedded in 1 for the first time, rapidly and on a gram-scale. | |
| dc.format.extent | 5 p. | |
| dc.format.mimetype | application/pdf | |
| dc.identifier.idgrec | 630295 | |
| dc.identifier.issn | 1359-7345 | |
| dc.identifier.uri | https://hdl.handle.net/2445/225192 | |
| dc.language.iso | eng | |
| dc.publisher | Royal Society of Chemistry | |
| dc.relation.isformatof | Versió postprint del document publicat a: https://doi.org/10.1039/c4cc01708k | |
| dc.relation.ispartof | Chemical Communications, 2014, vol. 50, p. 7099-7102 | |
| dc.relation.uri | https://doi.org/10.1039/c4cc01708k | |
| dc.rights | (c) Bradshaw, B. et al., 2014 | |
| dc.rights.accessRights | info:eu-repo/semantics/openAccess | |
| dc.subject.classification | Medicaments | |
| dc.subject.classification | Alcaloides | |
| dc.subject.classification | Síntesi orgànica | |
| dc.subject.other | Drugs | |
| dc.subject.other | Alkaloids | |
| dc.subject.other | Organic synthesis | |
| dc.title | A gram-scale route to phlegmarine alkaloids: rapid total synthesis of (-)-cermizine B | |
| dc.type | info:eu-repo/semantics/article | |
| dc.type | info:eu-repo/semantics/acceptedVersion |
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