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2023-01-23

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cc-by (c) Martín Vilardell, Anna et al., 2023
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/193374

Effect of Heat Treatment on Osteoblast Performance and Bactericidal Behavior of Ti6Al4V(ELI)-3at.%Cu Fabricated by Laser Powder Bed Fusion

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https://doi.org/10.3390/jfb14020063

Abstract

Cu addition to alloys for biomedical applications has been of great interest to reduce bac-terial growth. In situ-alloyed Ti6Al4V(ELI)-3at.%Cu was successfully manufactured by laser pow-der bed fusion (L-PBF). Even so, post-heat treatments are required to avoid distortions and/or achieve required/desired mechanical and fatigue properties. The present study is focused on the investigation of microstructural changes in L-PBF Ti6Al4V(ELI)-3at.%Cu after stress relieving and annealing treatments, as well as their influence on osteoblast and bactericidal behavior. After the stress relieving treatment, a homogenously distributed β phase and CuTi2 intermetallic precipitates were observed over the αʹ matrix. The annealing treatment led to the increase in amount and size of both types of precipitates, but also to phase redistribution along α lamellas. Although microstruc-tural changes were not statistically significant, such increase in β and CuTi2 content resulted in an increase in osteoblast proliferation after 14 days of cell culture. A significant bactericidal behavior of L-PBF Ti6Al4V(ELI)-3at.%Cu by means of ion release was found after the annealing treatment, provably due to the easier release of Cu ions from β phase. Biofilm formation was inhibited in all on Cu-alloyed specimens with stress relieving but also annealing treatment.

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Tractament tèrmic, Microestructura, Artrosi

Subject (English)

Heat treatment, Microstructure, Osteoarthritis

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Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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MARTÍN VILARDELL, Anna, et al. Effect of Heat Treatment on Osteoblast Performance and Bactericidal Behavior of Ti6Al4V(ELI)-3at.%Cu Fabricated by Laser Powder Bed Fusion. Journal of Functional Biomaterials . 2023. Vol. 14, num. 63. ISSN 2079-4983. [consulted: 9 of August of 2026]. Available at: https://hdl.handle.net/2445/193374

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