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Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops

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Cytosine-and guanine-rich regions of DNA are capable of forming complex structures named i-motifs and G-quadruplexes, respectively. In the present study the solution equilibria at nearly physiological conditions of a 34 -bases long cytosine-rich sequence and its complementary guanin e-rich strand corresponding to the first intron of the n-mycgene were studied. Both sequences , not yet studied, contain a 12 - base tract capable of forming stable hairpins inside the i-motif and G-quadruplex structures, respectively ...

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BENABOU ZDAOU, Sanae, FERREIRA AGUILERA, Rubén, AVIÑÓ ANDRÉS, Anna, GONZÁLEZ, Carlos, LYONNAIS, Sébastien, SOLÀ VILARRUBIAS, Maria, ERITJA I CASADELLÀ, Ramon, JAUMOT SOLER, Joaquim, GARGALLO GÓMEZ, Raimundo. Solution equilibria of cytosine- and guanine-rich sequences near the promoter region of the n-myc gene that contain stable hairpins within lateral loops. _Biochimica et Biophysica Acta-General Subjects_. 2013. [consulta: 20 de gener de 2026]. ISSN: 0304-4165. [Disponible a: https://hdl.handle.net/2445/46204]

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