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Molecular diagnostics for Chagas disease: up to date and novel methodologies
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Chagas disease is caused by the parasite Trypanosoma cruzi. It affects 7 million people, mainly in Latin America. Diagnosis is usually made serologically, but at some clinical scenarios serology cannot be used. Then, molecular detection is required for early detection of congenital transmission, treatment response follow up, and diagnosis of immune-suppression reactivation. However, present tests are technically demanding and require well-equipped laboratories which make them unfeasible in low-resources endemic regions.
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ALONSO PADILLA, Julio, et al. Molecular diagnostics for Chagas disease: up to date and novel methodologies. Expert Review Of Molecular Diagnostics. 2017. Vol. 17, num. 7, pags. 699-710. ISSN 1473-7159. [consulted: 19 of August of 2026]. Available at: https://hdl.handle.net/2445/204332