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GreenhouseB_Gates_Open_Res_2019.pdf (311.88 KB)

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2019-06-07

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cc by (c) Greenhouse et al., 2019
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/135362

Priority use cases for antibody-detecting assays of recent malaria exposure as tools to achieve and sustain malaria elimination

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http://dx.doi.org/10.12688/gatesopenres.12897.1

Resum

Measurement of malaria specific antibody responses represents a practical and informative method for malaria control programs to assess recent exposure to infection. Technical advances in recombinant antigen production, serological screening platforms, and analytical methods have enabled the identification of several target antigens for laboratory based and point-of-contact tests. Questions remain as to how these serological assays can best be integrated into malaria surveillance activities to inform programmatic decision-making. This report synthesizes discussions from a convening at Institut Pasteur in Paris in June 2017 aimed at defining practical and informative use cases for serology applications and highlights five programmatic uses for serological assays including: documenting the absence of transmission; stratification of transmission; measuring the effect of interventions; informing a decentralized immediate response; and testing and treating P. vivax hypnozoite carriers.

Matèries

Malària, Serodiagnòstic

Matèries (anglès)

Malaria, Serodiagnosis

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Articles publicats en revistes (ISGlobal)

Citació

GREENHOUSE, Bryan, DAILY, Jennifer, GUINOVART, Caterina, GONCALVES, Bronner, BEESON, James g., BELL, David, CHANG, Michelle a., COHEN, Justin m., DING, Xavier c., DOMINGO, Gonzalo, EISELE, Thomas p., LAMMIE, Patrick j., MAYOR APARICIO, Alfredo gabriel, MERIENNE, Nicolas, MONTEIRO, Wuelton marcelo, PAINTER, John, RODRÍGUEZ, Isabel, WHITE, Michael t., DRAKELEY, Chris, MUELLER, Ivo, Malaria Serology Convening. Priority use cases for antibody-detecting assays of recent
                malaria exposure as tools to achieve and sustain malaria
                elimination. _Gates Open Research_. 2019. Vol. 3, núm. 131. [consulta: 21 de gener de 2026]. ISSN: 2572-4754. [Disponible a: https://hdl.handle.net/2445/135362]

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