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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/185257
COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring
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Study of the effects of prenatal maternal infection on early offspring brain development has long attracted the interest and endeavors of clinicians and neuroscientists.1 Early reports on large-scale ecological data and further birth cohort studies analyzing biomarkers in pregnancy and early life of offspring have yielded evidence that in-utero exposure to infection increases neuropsychiatric disorder risk, particularly schizophrenia and autism spectrum disorders.2, 3, 4 The main hypothesis derived from these studies is that activation of immune-inflammatory pathways during maternal infection may result in abnormal fetal brain development.5 However, such a hypothesis requires detailed testing to reveal the pathogenic and pathophysiological mechanisms behind these neurodevelopmental alterations.
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AYESA-ARRIOLA, Rosa, LÓPEZ-DÍAZ, Álvaro, RUIZ-VEGUILLA, Miguel, LEZA, Juan carlos, FAÑANÁS SAURA, Lourdes, CRESPO-FACORRO, Benedicto. COVID-19 as a unique opportunity to unravel the link between prenatal maternal infection, brain development and neuropsychiatric disorders in offspring. _Revista de Psiquiatria y Salud Mental_. 2021. Vol. 14, núm. 1, pàgs. 1-3. [consulta: 4 de desembre de 2025]. ISSN: 1888-9891. [Disponible a: https://hdl.handle.net/2445/185257]