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2014-02-19

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cc-by (c) Merino Montero, Susana et al., 2014
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/61171

Gram-negative flagella glycosylation

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Recurs relacionat

http://dx.doi.org/10.3390/ijms15022840

Resum

Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one of these. Flagella O-glycosylation has been demonstrated in many polar flagellins from Gram-negative bacteria and in only the Gram-positive genera Clostridium and Listeria. Furthermore, O-glycosylation has also been demonstrated in a limited number of lateral flagellins. In this work, we revised the current advances in flagellar glycosylation from Gram-negative bacteria, focusing on the structural diversity of glycans, the O-linked pathway and the biological function of flagella glycosylation.

Matèries

Flagel·lats, Bacteris, Genètica bacteriana, Glicoproteïnes, Bacteris patògens

Matèries (anglès)

Flagellata, Bacteria, Bacterial genetics, Glycoproteins, Pathogenic bacteria

Citació

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Articles publicats en revistes (Genètica, Microbiologia i Estadística)

Citació

MERINO MONTERO, Susana and TOMÀS MAGAÑA, Juan. Gram-negative flagella glycosylation. International Journal of Molecular Sciences. 2014. Vol. 15, num. 2840-2857. ISSN 1422-0067. [consulted: 1 of July of 2026]. Available at: https://hdl.handle.net/2445/61171

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