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cc-by (c) Merino Montero, Susana et al., 2014
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/61171

Gram-negative flagella glycosylation

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Protein glycosylation had been considered as an eccentricity of a few bacteria. However, through advances in analytical methods and genome sequencing, it is now established that bacteria possess both N-linked and O-linked glycosylation pathways. Both glycosylation pathways can modify multiple proteins, flagellins from Archaea and Eubacteria being one of these. Flagella O-glycosylation has been demonstrated in many polar flagellins from Gram-negative bacteria and in only the Gram-positive genera Clostridium and Listeria. Furthermore, O-glycosylation has also been demonstrated in a limited number of lateral flagellins. In this work, we revised the current advances in flagellar glycosylation from Gram-negative bacteria, focusing on the structural diversity of glycans, the O-linked pathway and the biological function of flagella glycosylation.

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Citation

MERINO MONTERO, Susana and TOMÀS MAGAÑA, Juan. Gram-negative flagella glycosylation. International Journal of Molecular Sciences. 2014. Vol. 15, num. 2840-2857. ISSN 1422-0067. [consulted: 17 of August of 2026]. Available at: https://hdl.handle.net/2445/61171

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