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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/101652
The exposome in practice: Design of the EXPOsOMICS project
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Abstract
EXPOsOMICS is a European Union funded project that aims to
develop a novel approach to the assessment of exposure to high
priority environmental pollutants, by characterizing the
external and the internal components of the exposome. It focuses
on air and water contaminants during critical periods of life.
To this end, the project centres on 1) exposure assessment at
the personal and population levels within existing European
short and long-term population studies, exploiting available
tools and methods which have been developed for personal
exposure monitoring (PEM); and 2) multiple "omic" technologies
for the analysis of biological samples (internal markers of
external exposures). The search for the relationships between
external exposures and global profiles of molecular features in
the same individuals constitutes a novel advancement towards the
development of "next generation exposure assessment" for
environmental chemicals and their mixtures. The linkage with
disease risks opens the way to what are defined here as
'exposome-wide association studies' (EWAS).
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VINEIS, Paolo, et al. The exposome in practice: Design of the EXPOsOMICS project. International Journal of Hygiene and Environmental Health. 2016. pags. Ahead of print. ISSN 1438-4639. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/101652