Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/99544
Carriage prevalence of Salmonella enterica serotype Typhi in gallbladders of adult autopsy cases from Mozambique
Journal Title
Director/Tutor
Additional contribution
Journal ISSN
Volume Title
Abstract
INTRODUCTION: Typhoid fever is an important public health
problem in many low-income countries where asymptomatic carriers
play an important role in its dissemination. The bacterium
causing typhoid fever can live in the gallstones of asymptomatic
persons after the infection. These carriers are reservoirs of S.
Typhi, are highly contagious, and spread the disease through the
secretion of bacteria in feces and urine. The aim of this study
was to determine the carrier rate in an area of Mozambique.
METHODOLOGY: The presence of S. Typhi was analyzed in
gallbladder samples obtained from 99 adult corpses (in-hospital
deaths) from Mozambique by gold-standard culture and polymerase
chain reaction (PCR). RESULTS: Only one sample was positive with
the culture. However, nine additional samples were positive by
PCR and confirmed by DNA sequencing. Thus, the prevalence of S.
Typhi was 10.1% (10/99). CONCLUSIONS: We report a high
prevalence of S. Typhi in gallbladders among adult autopsy cases
from Mozambique.
Related resource
Subject
Subject (English)
Citation
Citation
LOVANE, Lucilia, et al. Carriage prevalence of Salmonella enterica serotype Typhi in
gallbladders of adult autopsy cases from Mozambique. Journal of Infection in Developing Countries. 2016. Vol. 10, num. 4, pags. 410-412. ISSN 1972-2680. [consulted: 10 of October of 2026]. Available at: https://hdl.handle.net/2445/99544