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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/176726
Ex vivo assessment and in vivo validation of non-invasive stent monitoring techniques based on microwave spectrometry
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Some conditions are well known to be directly associated with stent failure, including in-stent re-occlusion and stent fracture. Currently, identification of these high-risk conditions requires invasive and complex procedures. This study aims to assess microwave spectrometry (MWS) for monitoring stents non-invasively. Preliminary ex vivo data are presented to move to in vivo validation. Fifteen mice were assigned to receive subcutaneous stent implantations (n = 10) or sham operations (n = 5). MWS measurements were carried out at 0, 2, 4, 7, 14, 22, and 29 days of follow-up. Additionally, 5 stented animals were summited to micro-CT analyses at the same time points. At 29 days, 3 animals were included into a stent fracture subgroup and underwent a last MWS and micro-CT analysis. MWS was able to identify stent position and in-stent stenosis over time, also discerning significant differences from baseline measures (P < 0.001). Moreover, MWS identified fractured vs. non-fractured stents in vivo. Taken together, MWS emerges as a non-invasive, non-ionizing alternative for stent monitoring. MWS analysis clearly distinguished between in-stent stenosis and stent fracture phenomena.
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GÁLVEZ MONTÓN, Carolina, ARAUZ-GAROFALO, Gianluca, RODRÍGUEZ LEOR, Oriol, SOLER BOTIJA, Carolina, GARCÍA DE VALDECASAS, Susana amorós, GEREZ BRITOS, Flavio david, BAYÉS GENÍS, Antoni, O'CALLAGHAN, Juan manuel, MACIÀ BROS, Ferran, TEJADA PALACIOS, Javier. Ex vivo assessment and in vivo validation of non-invasive stent monitoring techniques based on microwave spectrometry. _Scientific Reports_. 2018. Vol. 8, núm. 1, pàgs. 14808. [consulta: 21 de gener de 2026]. ISSN: 2045-2322. [Disponible a: https://hdl.handle.net/2445/176726]