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Genomics and epigenomics of substance use disorders: An introduction

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Substance use disorders (SUD) are common conditions around theworld, with important health and societal impacts, particularly inthe burden of disease (disability-adjusted life years) (Whiteford, Fer-rari, Degenhardt, Feigin, & Vos, 2015). The Global Burden of DiseaseStudy estimated the global number of cases for SUD for several sub-stances as follows: 94.8 million for alcohol, 17.2 million for amphet-amine, 15.5 million for opioids, and 13.1 million for cannabis(Whiteford, 2015). In the United States, the lifetime and 12-monthprevalences of SUD were 9.9% and 3.9%, respectively (Grantet al., 2016). In addition, polysubstance use is an important challengein the field of addiction research (Whiteford et al., 2015).

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CORMAND RIFÀ, Bru, et al. Genomics and epigenomics of substance use disorders: An introduction. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics. 2021. Vol. 186, num. 3, pags. 125-127. ISSN 1552-4841. [consulted: 26 of May of 2026]. Available at: https://hdl.handle.net/2445/194643

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