The Evaluation of Optic Nerves Using 7 Tesla 'Silent' Zero Echo Time Imaging in Patients with Leber's Hereditary Optic Neuropathy with or without Idebenone Treatment

Vista senzilla d'ítem
dc.contributor.authorGrochowski, Cezary
dc.contributor.authorSymms, Mark
dc.contributor.authorJonak, Kamil
dc.contributor.authorKrukow, Pawel
dc.contributor.authorWood, Tobias C.
dc.contributor.authorLjungberg, Emil
dc.contributor.authorEnseñat Nora, Joaquim
dc.contributor.authorNowomiejska, Katarzyna
dc.contributor.authorRejdak, Robert
dc.contributor.authorMaciejewski, Ryszard
dc.contributor.authorBarker, Gareth J.
dc.date.accessioned2021-04-16T08:32:44Z
dc.date.available2021-04-16T08:32:44Z
dc.date.issued2020-04-13
dc.date.updated2021-04-16T08:32:44Z
dc.description.abstractMagnetic Resonance Imaging (MRI) of the Optic Nerve is difficult due to the fine extended nature of the structure, strong local magnetic field distortions induced by anatomy, and large motion artefacts associated with eye movement. To address these problems we used a Zero Echo Time (ZTE) MRI sequence with an Adiabatic SPectral Inversion Recovery (ASPIR) fat suppression pulse which also imbues the images with Magnetisation Transfer contrast. We investigated an application of the sequence for imaging the optic nerve in subjects with Leber's hereditary optic neuropathy (LHON). Of particular note is the sequence's near-silent operation, which can enhance image quality of the optic nerve by reducing the occurrence of involuntary saccades induced during Magnetic Resonance (MR) scanning.
dc.format.extent13 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec708231
dc.identifier.issn2077-0383
dc.identifier.pmid32295018
dc.identifier.urihttps://hdl.handle.net/2445/176372
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/jcm9041112
dc.relation.ispartofJournal of Clinical Medicine, 2020, vol. 9, num. 4, p. 1112
dc.relation.urihttps://doi.org/10.3390/jcm9041112
dc.rightscc-by (c) Grochowski, Cezary et al., 2020
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)
dc.subject.classificationRessonància magnètica
dc.subject.classificationNervi òptic
dc.subject.otherMagnetic resonance
dc.subject.otherOptic nerve
dc.titleThe Evaluation of Optic Nerves Using 7 Tesla 'Silent' Zero Echo Time Imaging in Patients with Leber's Hereditary Optic Neuropathy with or without Idebenone Treatment
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
708231.pdf
Mida:
2.14 MB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Cirurgia i Especialitats Medicoquirúrgiques)