Miniatura

Fitxers

705571.pdf (8.83 MB)

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

2019-11-07

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/173141

The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1111/acps.13114

Resum

Background A higher incidence of childhood trauma (CT) has been reported in first episode of psychosis (FEP). There is, however, a lack of knowledge about the synergetic effect between CT and recent stressful events (RSE). Methods Information on specific types of CT (under 17 years) and RSE (within the past 3 years) was available for 290 FEP patients and 52 healthy controls (HC). Cognitive function at baseline was assessed through a comprehensive neuropsychological test battery. Results While 45.2% of FEP patients and 25% of HC reported at least one CT event, 62.7% of FEP and 21.2% of HC reported an RSE. Meanwhile, 36.2% of FEP patients and 9.6% of HC encountered both childhood and recent stressful events. The patients that just reported CT showed normality in all but the verbal memory cognitive domain; those with additive CT and RSE presented worse general cognitive function, specifically on working memory, processing speed, and executive function. RSE and general cognitive dysfunction were significant determinants of psychosis onset. Conclusions These results support a synergetic influence of trauma and stressful events on brain function and allow a better understanding of mediators for psychotic disorders useful in the design of specific strategies based on stress‐targeted therapies.

Matèries

Traumes psíquics, Malalties mentals, Infants

Matèries (anglès)

Psychic trauma, Mental illness, Children

Citació

Col·leccions

Articles publicats en revistes (Biologia Evolutiva, Ecologia i Ciències Ambientals)

Citació

AYESA ARRIOLA, Rosa, SETIÉN-SUERO, E., MARQUES-FEIXA, Laia, NEERGAARD, Karl, BUTJOSA, A., VÁZQUEZ-BOURGON, J., FAÑANÁS SAURA, Lourdes, CRESPO FACORRO, Benedicto. The synergetic effect of childhood trauma and recent stressful events in psychosis: associated neurocognitive dysfunction. _Acta Psychiatrica Scandinavica_. 2019. Vol. 141, núm. 1, pàgs. 43-51. [consulta: 24 de gener de 2026]. ISSN: 0001-690X. [Disponible a: https://hdl.handle.net/2445/173141]

Exportar metadades

JSON - METS

Compartir registre