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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/223100
Deep Learning Tools for image classification in Cryo-electron microscopy
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Cryo-electron microscopy is an imaging technique used for 3D reconstruction of biomolecules, enabling researchers to study their structures. However, due to low signal-to-noise ratios in captured images, 2D classification is a critical preprocessing step. This thesis explores the application of a deep learning approach, specifically a similarity network, to address this challenge.
A Siamese model, trained with a Triplet Loss function, is used to differentiate between similar and dissimilar images. The model was trained on a dataset with known ground truth and tested on two types of unseen data: a similar dataset with ground truth and a different dataset without the ground truth. This study demonstrates the potential of deep learning to complement traditional 2D classification methods in cryo-EM.
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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2025, Tutor: David Maluenda
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LORENZANA SANTUYO, Joshua. Deep Learning Tools for image classification in Cryo-electron microscopy. [consulta: 22 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/223100]