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1989

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cc-by-nc-nd (c) Barbé García, Jordi et al., 1989
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/127322

Modulació de la inducció del sistema d'emergència (SOS) en Escherichia coli per la regío amino-terminal de la proteïna RecA.

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Abstract

The amino-terminal fragment of the RecA protein was cloned in pUA27 plasmid and introduced in different repair mutants of Escherichia coli. The UV-mediated induction of several SOS functions was then studied. Results show that the truncated RecA protein plays an important role in the UV-damaged DNA when the level of the chromosomal RecA protein is low. Furthermore, RecA protein inhibited the protease activity of the wild type RecA protein causing a decrease in the SOS system induction. All these data suggest that hybrid tetramers between both truncated and wild type RecA proteins may be formed, and as a consequence the ATPase capacity and active conformation of the wild type RecA protein are blocked.

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Duplicació de l'ADN, Escheríchia coli, Reparació de l'ADN

Subject (English)

DNA replication, Escherichia coli, DNA repair

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Articles publicats en revistes (Genètica, Microbiologia i Estadística)

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BARBÉ GARCÍA, Jordi, et al. Modulació de la inducció del sistema d'emergència (SOS) en Escherichia coli per la regío amino-terminal de la proteïna RecA. Treballs de la Societat Catalana de Biologia. 1989. Vol. 40, num. 33-46. ISSN 0212-3037. [consulted: 19 of August of 2026]. Available at: https://hdl.handle.net/2445/127322

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