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Published version

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2021-09-08

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cc-by (c) Llorens-Giralt, Palmira et al., 2021
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/186605

Chromatin organization and function in Drosophila

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https://doi.org/10.3390/cells10092362

Abstract

Eukaryotic genomes are packaged into high-order chromatin structures organized in discrete territories inside the cell nucleus, which is surrounded by the nuclear envelope acting as a barrier. This chromatin organization is complex and dynamic and, thus, determining the spatial and temporal distribution and folding of chromosomes within the nucleus is critical for understanding the role of chromatin topology in genome function. Primarily focusing on the regulation of gene expression, we review here how the genome of Drosophila melanogaster is organized into the cell nucleus, from small scale histone-DNA interactions to chromosome and lamina interactions in the nuclear space.

Subject

Regulació genètica, Cromatina, Drosòfila

Subject (English)

Genetic regulation, Chromatin, Drosophila

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Articles publicats en revistes (Genètica, Microbiologia i Estadística)

Citation

LLORENS-GIRALT, Palmira, et al. Chromatin organization and function in Drosophila. Cells. 2021. Vol. 10, num. 9, pags. 2362. ISSN 2073-4409. [consulted: 11 of August of 2026]. Available at: https://hdl.handle.net/2445/186605

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