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A measure of stability as a criterion for the verification and analysis of simulation models

dc.contributor.authorMonleón Getino, Tonicat
dc.contributor.authorRuiz de Villa, Carmencat
dc.contributor.authorOcaña i Rebull, Jordicat
dc.date.accessioned2010-04-20T11:14:46Z-
dc.date.available2010-04-20T11:14:46Z-
dc.date.issued2010-
dc.description.abstractThe aim of this study is to define a new statistic, PVL, based on the relative distance between the likelihood associated with the simulation replications and the likelihood of the conceptual model. Our results coming from several simulation experiments of a clinical trial show that the PVL statistic range can be a good measure of stability to establish when a computational model verifies the underlying conceptual model. PVL improves also the analysis of simulation replications because only one statistic is associated with all the simulation replications. As well it presents several verification scenarios, obtained by altering the simulation model, that show the usefulness of PVL. Further simulation experiments suggest that a 0 to 20 % range may define adequate limits for the verification problem, if considered from the viewpoint of an equivalence test.eng
dc.format.extent30 p.-
dc.format.mimetypeapplication/pdf-
dc.identifier.urihttps://hdl.handle.net/2445/12194-
dc.language.isoeng-
dc.rightscc-by-nc-nd, (c) Monleon et al., 2010-
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/-
dc.sourceDocuments de treball / Informes (Genètica, Microbiologia i Estadística)
dc.subject.classificationSimulació per ordinadorcat
dc.subject.classificationModels matemàticscat
dc.subject.classificationMètodes estadísticscat
dc.subject.classificationAssaigs clínicscat
dc.subject.otherComputer simulationeng
dc.subject.otherMathematical modelseng
dc.subject.otherStatistical methodseng
dc.subject.otherClinical trialseng
dc.titleA measure of stability as a criterion for the verification and analysis of simulation modelseng
dc.typeinfo:eu-repo/semantics/workingPaper-

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