E2F4/5-mediated transcriptional control of multiciliated cell differentiation: redundancy or fine-tuning?

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dc.contributor.authorStracker, Travis H.
dc.date.accessioned2019-09-23T13:05:03Z
dc.date.available2019-12-08T06:10:19Z
dc.date.issued2018-12-08
dc.date.updated2019-09-16T13:49:49Z
dc.description.abstractCentrosomes consist of a pair of cylindrical, microtubule based structures called centrioles, surrounded by proteinaceous pericentriolar material (Nigg and Holland, 2018). Centrosomes are key regulators of mitotic spindle formation and the docking of one of the centrioles on the cell surface allows it to function as a basal body for primary cilium formation. In interphase cells, similar to DNA replication, the mother centriole-dependent (MCD) pathway of duplication is regulated to occur once per cell cycle in order to ensure monociliation and prevent abnormal mitoses resulting from spindle defects caused by numerical aberrations in centrosomes (Nigg and Holland, 2018).ca
dc.format.extent4 p.
dc.format.mimetypeapplication/pdf
dc.identifier.pmid30537487
dc.identifier.urihttps://hdl.handle.net/2445/140741
dc.language.isoengca
dc.publisherElsevierca
dc.relation.isformatofVersió postprint del document publicat a: http://dx.doi.org/10.1016/j.ydbio.2018.12.007
dc.relation.ispartofDevelopmental Biology, 2019, vol. 446, num. 1, p. 20-21
dc.relation.urihttp://dx.doi.org/10.1016/j.ydbio.2018.12.007
dc.rightscc by-nc-nd (c) Elsevier, 2019
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.sourceArticles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))
dc.subject.classificationMicrotúbuls
dc.subject.classificationCicle cel·lular
dc.subject.otherMicrotubules
dc.subject.otherCell cycle
dc.titleE2F4/5-mediated transcriptional control of multiciliated cell differentiation: redundancy or fine-tuning?ca
dc.typeinfo:eu-repo/semantics/articleca
dc.typeinfo:eu-repo/semantics/acceptedVersion

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