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2019-06-01

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cc-by-nc-nd (c) Elsevier, 2019
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/154417

Metabolomics in systems medicine: an overview of methods and applications

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https://doi.org/10.1016/j.coisb.2019.03.009

Abstract

Patient-derived metabolomics offers valuable insights into the metabolic phenotype underlying diseases with a strong metabolic component. Thus, these data sets will be pivotal to the implementation of personalized medicine strategies in health and disease. However, to take full advantage of such data sets, they must be integrated with other omics within a coherent pathophysiological framework to enable improved diagnostics, to identify therapeutic interventions, and to accurately stratify patients. Herein, we provide an overview of the state-of-the-art data analysis and modeling approaches applicable to metabolomics data and of their potential for systems medicine.

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Metabolòmica

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Metabolomics

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Articles publicats en revistes (Bioquímica i Biomedicina Molecular)

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KARAKITSOU, Effrosyni, et al. Metabolomics in systems medicine: an overview of methods and applications. Current Opinion in Systems Biology. 2019. Vol. 15, num. 91-99. ISSN 2452-3100. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/154417

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