Files
Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/109284
Comparative genomics of the Aeromonadaceae core oligosaccharide biosynthetic regions.
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
Lipopolysaccharides (LPSs) are an integral part of the Gram-negative outer membrane, playing important organizational and structural roles and taking part in the bacterial infection process. In Aeromonas hydrophila, piscicola, and salmonicida, three different genomic regions taking part in the LPS core oligosaccharide (Core-OS) assembly have been identified, although the characterization of these clusters in most aeromonad species is still lacking. Here, we analyse the conservation of these LPS biosynthesis gene clusters in the all the 170 currently public Aeromonas genomes, including 30 different species, and characterise the structure of a putative common inner Core-OS in the Aeromonadaceae family. We describe three new genomic organizations for the inner Core-OS genomic regions, which were more evolutionary conserved than the outer Core-OS regions, which presented remarkable variability. We report how the degree of conservation of the genes from the inner and outer Core-OS may be indicative of the taxonomic relationship between Aeromonas species.
Subject
Subject (English)
Citation
Citation
FORN-CUNÍ, Gabriel, TOMÀS MAGAÑA, Juan and MERINO MONTERO, Susana. Comparative genomics of the Aeromonadaceae core oligosaccharide biosynthetic regions. International Journal of Molecular Sciences. 2017. Vol. 18, num. 519-531. ISSN 1422-0067. [consulted: 9 of August of 2026]. Available at: https://hdl.handle.net/2445/109284