Validation and optimization of omnipolar technology in ventricular ablation procedures

Abstract

This project aims to improve the effectiveness of ventricular tachycardia (VT) ablation procedures by accurately mapping the reentrant channels responsible for the arrhythmia. The study compares different mapping techniques, including bipolar, orthogonal, and omnipolar signals, using the HD Grid catheter and the EnSite X system. Electro-Anatomical Maps (EAMs) created through these techniques are evaluated for their accuracy in identifying channels by comparing them with Cardiac Magnetic Resonance (CMR) maps. The project's findings demonstrate that the omnipolar map, optimized with specific thresholds, exhibits higher correlation with the CMR map, offering reliable and accurate information about the cardiac tissue. Moreover, the comparisons are done also between layers of the ventricle’s heart, the layer 50 (which is an average of the pixels of layers 10- 50) is identified as the most informative layer, and expanded maximum thresholds allow for a comprehensive understanding of ventricular tissue. The results validate the superiority of the omnipolar technology and emphasize the need for further research and collaboration to advance the field of VT ablation procedures.