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2017-07-24

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/115797

Evidence-Based Guidelines for Screening and Management of Strongyloidiasis in Non-Endemic Countries

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http://dx.doi.org/10.4269/ajtmh.16-0923

Abstract

Strongyloidiasis is an intestinal parasitic infection becoming increasingly important outside endemic areas, not only because of the high prevalence found in migrant populations, but also because immunosuppressed patients may suffer a potentially fatal disseminated disease. The aim of these guidelines is to provide evidence-based guidance for screening and treatment of strongyloidiasis in non-endemic areas. A panel of experts focused on three main clinical questions (who should be screened and how, how to treat), and reviewed pertinent literature available in international databases of medical literature and in documents released by relevant organizations/societies. A consensus of the experts' opinion was sought when specific issues were not covered by evidence. In particular, six systematic reviews were retrieved and constituted the main support for this work. The evidence and consensus gathered led to recommendations addressing various aspects of the main questions. Grading of evidence and strength of recommendation were attributed to assess the quality of supporting evidence. The screening of individuals at risk of the infection should be performed before they develop any clinical complication. Moreover, in immunosuppressed patients, the screening should be mandatory. The screening is based on a simple and widely accessible technology and there is now a universally accepted treatment with a high efficacy rate. Therefore, the screening could be implemented as part of a screening program for migrants although further cost-effectiveness studies are required to better evaluate this strategy from a public health point of view.

Subject

Nematodes, Malalties infeccioses

Subject (English)

Nematodes, Communicable diseases

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Articles publicats en revistes (ISGlobal)

Citation

REQUENA-MÉNDEZ, Ana, et al. Evidence-Based Guidelines for Screening and Management of
                Strongyloidiasis in Non-Endemic Countries. The American Journal of Tropical Medicine and Hygiene. 2017. Vol. 97, num. 3, pags. 645-652. ISSN 0002-9637. [consulted: 16 of June of 2026]. Available at: https://hdl.handle.net/2445/115797

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