Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/176779
Renal size and cardiovascular risk in prepubertal children
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Renal size is an important parameter for the evaluation and diagnosis of kidney disease and has been associated with several cardiovascular risk factors in patients with kidney failure. These results are however discordant and studies in healthy children are lacking. We aimed to study the association between renal size (length and volume) and cardiovascular risk parameters in healthy children. Clinical, analytical and ultrasound parameters [renal length, renal volume, perirenal fat and carotid intima-media thickness (cIMT)] were determined in 515 healthy prepubertal children (176 lean, 208 overweight and 131 obese). Renal length and volume associated significantly and positively with several anthropometric and cardiovascular risk parameters including cIMT and systolic blood pressure (SBP) (all p < 0.001). Renal length and volume associated with cIMT and SBP in all study subgroups, but these associations were predominant in obese children, in whom these associations were independent after adjusting for age, gender and BSA (all p < 0.05). In multivariate analyses in the study subjects as a whole, renal length was an independent predictor of cIMT (β = 0.310, p < 0.0001) and SBP (β = 0.116, p = 0.03). Renal size associates with cIMT and SBP, independent of other well-established cardiovascular risk factors, and may represent helpful parameters for the early assessment of cardiovascular risk in children.
Matèries (anglès)
Citació
Citació
LIZARRAGA MOLLINEDO, Esther, MARTÍNEZ CALCERRADA, José maría, PADRÓS FORNIELES, Cristina, MAS PARES, Berta, XARGAY I TORRENT, Sílvia, RIERA PÉREZ, Elena, PRATS PUIG, Anna, CARRERAS BADOSA, Gemma, DE ZEGHER, Francis, IBÁÑEZ TODA, Lourdes, BASSOLS, Judit, LÓPEZ BERMEJO, Abel. Renal size and cardiovascular risk in prepubertal children. _Scientific Reports_. 2019. Vol. 9, núm. 1, pàgs. 5265. [consulta: 24 de gener de 2026]. ISSN: 2045-2322. [Disponible a: https://hdl.handle.net/2445/176779]