Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Tots els drets reservats
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/124269
Application of microsatellite genotyping to the study of a restricted Leishmania infantum focus: different genotype compositions in isolates from dogs and sand flies
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
Leishmania infantum polymorphism was studied by DNA microsatellite analysis of 110 L. infantum stocks (94 from dogs, 15 from sand flies, and 1 from a human visceral case) from a rural leishmaniasis-endemic area (Priorat) in northeastern Spain. Three microsatellites of the eight present in three fragments (internal transcribed spacer, Lm4, and Lm2) of L. infantum nuclear DNA are polymorphic inside the focus, resulting in 17 genotypes. Isolates from dogs and sand flies had different allelic compositions and shared only four genotypes. Microsatellite analysis is useful for L. infantum genotyping and epidemiologic tracking. Its application with strains from dogs and vectors in an area endemic for leishmaniasis shows the heterogeneous distribution of L. infantum in hosts living in sympatric conditions.
Matèries
Matèries (anglès)
Citació
Citació
MONTOYA, Liliana, GÁLLEGO CULLERÉ, M. (montserrat), GAVIGNET, Béatrice, PIARROUX, Renaud, RIOUX, Jean-antoine, PORTÚS VINYETA, Montserrat, FISA SALADRIGAS, Roser. Application of microsatellite genotyping to the study of a restricted Leishmania infantum focus: different genotype compositions in isolates from dogs and sand flies. _American Journal of Tropical Medicine and Hygiene_. 2007. Vol. 76, núm. 5, pàgs. 888-895. [consulta: 23 de gener de 2026]. ISSN: 0002-9637. [Disponible a: https://hdl.handle.net/2445/124269]