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12541_6456794_centrosomes_in_asymmetric_cell_division.pdf (491.31 KB)

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Article

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Accepted version

Publication date

2020-12-03

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/172667

Centrosomes in asymmetric cell division

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https://doi.org/10.1016/j.sbi.2020.10.023

Abstract

Asymmetric cell division (ACD) is a strategy for achieving cell diversity. Research carried out over the last two decades has shown that in some cell types that divide asymmetrically, mother and daughter centrosomes are noticeably different from one another in structure, behaviour, and fate, and that robust ACD depends upon centrosome function. Here, I review the latest advances in this field with special emphasis on the complex structure-function relationship of centrosomes with regards to ACD and on mechanistic insight derived from cell types that divide symmetrically but is likely to be relevant in ACD. I also include a comment arguing for the need to investigate the centrosome cycle in other cell types that divide asymmetrically.

Subject

Divisió cel·lular, Microtúbuls

Subject (English)

Cell division, Microtubules

Citation

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Articles publicats en revistes (Institut de Recerca Biomèdica (IRB Barcelona))

Citation

GONZÁLEZ, Cayetano. Centrosomes in asymmetric cell division. Current Opinion in Structural Biology. 2021. Vol. 66, num. 178-182. ISSN 6456794. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/172667

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