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2004-06-01

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A synthetic alternative to natural lecithins with antimicrobial properties

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Recurs relacionat

https://doi.org/10.1016/j.colsurfb.2004.03.014

Resum

Two soft biocompatible cationic surfactants from the amino acid arginine, 1,2-dilauroyl-3-acetylarginyl-rac-glycerol (1212RAc) and 1,2-dimirystoyl-3-acetylarginyl-rac-glycerol (1414RAc), were prepared. Their physicochemical properties show that they can be classified as multifunctional surfactants with self-aggregation behaviour comparable to that of short-chain lecithins. The two surfactants can simultaneously stabilise water-in-oil (W/O) droplets and oil-in-water (O/W) droplets, forming multiple emulsions. They have antimicrobial activity similar to that of conventional cationic surfactants and are as harmless as amphoteric betaines. These surfactants constitute an interesting alternative to the diglycerides and lecithins in formulations that require antimicrobial properties.

Matèries

Síntesi orgànica, Interfícies biològiques, Agents antiinfecciosos, Agents tensioactius, Emulsions, Bioquímica analítica

Matèries (anglès)

Organic synthesis, Biological interfaces, Anti-infective agents, Surface active agents, Emulsions, Analytical biochemistry

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Articles publicats en revistes (Bioquímica i Fisiologia)

Citació

PÉREZ, L., et al. A synthetic alternative to natural lecithins with antimicrobial properties. Colloids and Surfaces B-Biointerfaces. 2004. Vol. 35, num. 3-4, pags. 235-242. ISSN 0927-7765. [consulted: 24 of May of 2026]. Available at: https://hdl.handle.net/2445/127861

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