Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/104278
Life at the mesoscale: the self-organised cytoplasm and nucleoplasm
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
Abstract The cell contains highly dynamic structures exploiting physical principles of self-organisation at the mesoscale (100 nm to 10 μ m). Examples include non-membrane bound cytoplasmic bodies, cytoskeleton-based motor networks and multi-scale chromatin organisation. The challenges of mesoscale self-organisation were discussed at a CECAM workshop in July 2014. Biologists need approaches to observe highly dynamic, low affinity, low specificity associations and to perturb single structures, while biological physicists and biomathematicians need to work closely with biologists to build and validate quantitative models. A table of terminology is included to facilitate multidisciplinary efforts to reveal the richness and diversity of mesoscale cell biology. Keywords: Workshop report, Self-organisation, Mesoscale, Cell biology, Cytoskeleton, Cytoplasmic bodies, Chromatin
Subject
Subject (English)
Citation
Citation
SEAR, Richard P., PAGONABARRAGA MORA, Ignacio and FLAUS, Andrew. Life at the mesoscale: the self-organised cytoplasm and nucleoplasm. BMC Biophysics. 2015. Vol. 8, num. 4. ISSN 2046-1682. [consulted: 13 of June of 2026]. Available at: https://hdl.handle.net/2445/104278