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924835.pdf (328.65 KB)

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2025-07-31

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cc-by-nc-nd (c) Elsevier Ltd., 2025
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/227506

Pre-COPD: an evolving concept with practice potential

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Recurs relacionat

https://doi.org/10.1016/S2213-2600(25)00236-X

Resum

COPD is the third leading cause of death globally and remains a major public health burden. Despite its substantial impact, effective prevention remains challenging. COPD is currently defined as having FEV1/FVC below lower limit of normal or 0.7 in a person with known risk factors. However, this formal diagnosis occurs only after significant loss of lung function and the onset of persistent symptoms. These symptoms, rather than pathophysiological changes, are what typically prompt patients to seek medical care. Even then, many are not offered spirometry, further delaying diagnosis until acute exacerbations or a level of dyspnoea that impacts daily life prompt clinical attention. By this point, more than 50% of individual’s FEV1 has often been lost and treatment becomes largely palliative. This situation highlights a pressing need for earlier identification of lung damage associated to a later diagnosis of COPD; this is needed in its early “silent” phase, when there might be an opportunity to change the course of disease with preventive interventions.

Matèries

Malalties pulmonars obstructives cròniques, Salut pública

Matèries (anglès)

Chronic obstructive pulmonary diseases, Public health

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Articles publicats en revistes (Biomedicina)

Citació

BUI, Dinh S., et al. Pre-COPD: an evolving concept with practice potential. The Lancet Respiratory Medicine. 2025. Vol. 13, num. 9, pags. 778-781. ISSN 2213-2600. [consulted: 5 of August of 2026]. Available at: https://hdl.handle.net/2445/227506

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