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malerarefreshconsultativepanelonbasicscienceandenablingtechnologies2017_2860.pdf (3.05 MB)

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2017-11-30

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cc by (c) malERA Refresh Consultative Panel on Basic Science and Enabling Technologies, 2017
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/119649

malERA: An updated research agenda for basic science and enabling technologies in malaria elimination and eradication

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http://dx.doi.org/10.1371/journal.pmed.1002451

Abstract

Basic science holds enormous power for revealing the biological mechanisms of disease and, in turn, paving the way toward new, effective interventions. Recognizing this power, the 2011 Research Agenda for Malaria Eradication included key priorities in fundamental research that, if attained, could help accelerate progress toward disease elimination and eradication. The Malaria Eradication Research Agenda (malERA) Consultative Panel on Basic Science and Enabling Technologies reviewed the progress, continuing challenges, and major opportunities for future research. The recommendations come from a literature of published and unpublished materials and the deliberations of the malERA Refresh Consultative Panel. These areas span multiple aspects of the Plasmodium life cycle in both the human host and the Anopheles vector and include critical, unanswered questions about parasite transmission, human infection in the liver, asexual-stage biology, and malaria persistence. We believe an integrated approach encompassing human immunology, parasitology, and entomology, and harnessing new and emerging biomedical technologies offers the best path toward addressing these questions and, ultimately, lowering the worldwide burden of malaria.

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Malària, Malalties parasitàries

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Malaria, Parasitic diseases

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malERA Refresh Consultative Panel on Basic Science and Enabling Technologies and RABINOVICH, Regina. malERA: An updated research agenda for basic science and
                enabling technologies in malaria elimination and eradication. PLoS Medicine. 2017. Vol. 14, num. 11, pags. e1002451. ISSN 1549-1277. [consulted: 14 of August of 2026]. Available at: https://hdl.handle.net/2445/119649

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