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Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platform
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Three-dimensional porous Co-Ni films/alginate hybrid materials have been successfully prepared by electrodeposition to be used as a steerable magnetic device for drug delivery. Firstly, 3D porous Co-Ni films were prepared as substrates for the subsequent electrodeposition of the alginate biopolymer. Cyclic voltammetry, galvanostatic and potentiostatic studies were performed to establish the best conditions to obtain porous Co-Ni films. The electrochemical experiments were carried out in an electrolyte containing the metal salts and ammonium chloride at low pHs. In a second stage, the electrochemical deposition of alginate as a biocompatible polymer drug delivery carrier was performed. The characteristics of the alginate matrix were investigated in terms of electrochemical properties, morphology and drug release. The hybrid material obtained showed soft-magnetic behavior and drug release indicating its suitability to be used as a steerable magnetic drug delivery device.
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GARCÍA-TORRES, José, et al. Alginate electrodeposition onto three-dimensional porous Co-Ni films as drug delivery platform. Physical Chemistry Chemical Physics. 2015. Vol. 17, num. 1630-1636. ISSN 1463-9076. [consulted: 28 of June of 2026]. Available at: https://hdl.handle.net/2445/139935