Miniatura

Fitxers

535747.pdf (3.4 MB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

1997-03-01

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/177301

Evaluation of renographic and metabolic parameters in human Kidney transplantation

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

Resum

Background: the aim of this work is to demonstrate that the value of the mean transit time (MTT) obtained from the 99mTc-MAG3 renogram deconvolution is related to the levels of adenine nucleotides determined in cortical biopsies from transplanted kidneys. Methods: the functional state was estimated by means of the MTT and the initial height (H0) of the renal retention function obtained from the 99mTc-MAG3 renogram deconvolution and by the measure of adenine nucleotides obtained from biopsies. We studied 30 kidney graft recipients, 25 normal functioning grafts (NFG) and 5 with acute tubular necrosis (ATN). Results: the MTT is significantly longer for ATN (p < 0.001). The initial uptake values (H0) are significantly lower for ATN (p < 0.001). The sum of adenine nucleotides (SAN) is significantly greater for NFG than for ATN (p < 0.001). The values of the MTT seem to reflect the energy state of the cells in transplanted kidney. Conclusion: the analysis of MTT may be indicative of the functional metabolic recovery and thus it may be predictive of the renal graft function at least in the same extent than the biochemical analysis of a cortical renal biopsy immediately after blood reperfusion of the tissue.

Matèries

Trasplantament renal, Diagnòstic per la imatge, Metabolisme

Matèries (anglès)

Kidney transplantation, Diagnostic imaging, Metabolism

Citació

Col·leccions

Articles publicats en revistes (Ciències Fisiològiques)
Articles publicats en revistes (Ciències Clíniques)

Citació

GONZÁLEZ SISTAL, Ángel, VIGUÉS I JULIÀ, Francesc, PUCHAL AÑÉ, Rafael, FRANCO MIRANDA, Eladio, BARTRONS BACH, Ramon, AMBROSIO VIALE, Santiago. Evaluation of renographic and metabolic parameters in human Kidney transplantation. _Journal of Nuclear Medicine_. 1997. Vol. 41, núm. 1, pàgs. 42-45. [consulta: 21 de gener de 2026]. ISSN: 0161-5505. [Disponible a: https://hdl.handle.net/2445/177301]

Exportar metadades

JSON - METS

Compartir registre