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Treball de fi de grau

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cc-by-nc-nd (c) Hernàndez Arnal, Violeta, 2026
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/231419

Modelling the epidemiological impact of diagnostic performance on malaria transmission: a multi-scale approach

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Malaria is one of the leading causes of preventable death worldwide, yet the epidemiological impact of diagnostic performance on the transmission dynamics is poorly understood. Three models of increasing complexity are studied: a single-strain model, a two-strain model and a spatially distributed model in order to quantify how the choice of the diagnostic method and the geographical distribution of healthcare centers affect the prevalence of the disease. The results of the study show that Rapid Diagnosis Tests (RDT) present a blind spot that allows the mutated variant to circulate silently at high prevalence levels, a phenomenon suppressed when changing the diagnostic method to microscopy. The spatial analysis demonstrates that diagnostic quality has a stronger influence on endemic prevalence rather than the size of the healthcare network.

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2016, Tutors: Daniel López Codina, Clara Prats i Soler, Marta Ibañes Miguez

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HERNÀNDEZ ARNAL, Violeta. Modelling the epidemiological impact of diagnostic performance on malaria transmission: a multi-scale approach. [consulted: 11 of September of 2026]. Available at: https://hdl.handle.net/2445/231419

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