Innovative Strategies for Photoallergy Assessment: Breaking Free from Animal Models in Cosmetic Ingredient Development

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dc.contributor.authorVinardell Martínez-Hidalgo, Ma. Pilar
dc.contributor.authorMaddaleno Jiménez, Adriana Solange
dc.contributor.authorMitjans Arnal, Montserrat
dc.date.accessioned2024-04-05T08:34:26Z
dc.date.available2024-04-05T08:34:26Z
dc.date.issued2024-03-25
dc.date.updated2024-04-05T08:34:31Z
dc.description.abstract<p>Photoallergy, a unique form of skin sensitization induced by specific compounds under</p><p>ultraviolet irradiation, has traditionally been investigated using animals. However, the prohibition of</p><p>animal testing for the assessment of cosmetic ingredients in Europe and other countries underscores</p><p>the necessity for in vitro or in silico alternative methods. Currently, there are no validated methods for</p><p>assessing photoallergy or photosensitization, presenting a significant challenge in the development of</p><p>new cosmetic ingredients. This review examines the landscape of alternative methods for detecting</p><p>photosensitization, emphasizing recent publications, and considering the underlying principles of</p><p>the different proposed assays.</p>
dc.format.extent1 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec747604
dc.identifier.issn2079-9284
dc.identifier.urihttps://hdl.handle.net/2445/209387
dc.language.isoeng
dc.publisherMDPI
dc.relation.isformatofReproducció del document publicat a: https://doi.org/https://doi.org/10.3390/cosmetics11020047
dc.relation.ispartofCosmetics, 2024, vol. 11, num.2, p. 47
dc.relation.urihttps://doi.org/https://doi.org/10.3390/cosmetics11020047
dc.rightscc-by (c) Maddaleno, A.S. et al., 2024
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/
dc.sourceArticles publicats en revistes (Bioquímica i Fisiologia)
dc.subject.classificationAl·lèrgia
dc.subject.classificationPell
dc.subject.classificationCosmètics
dc.subject.classificationExperimentació animal
dc.subject.otherAllergy
dc.subject.otherSkin
dc.subject.otherCosmetics
dc.subject.otherAnimal experimentation
dc.titleInnovative Strategies for Photoallergy Assessment: Breaking Free from Animal Models in Cosmetic Ingredient Development
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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