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Bachelor thesis

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cc-by-nc-nd (c) Mayordomo, 2017
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/117591

Dynamics of vesicle and cell membranes driven by pressure differences

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Abstract

Cell size and shape can be modified by hydrostatic pressure differences between both sides of its membrane. In order to analyze its behavior, two simplified models are evaluated. A model for vesicle expansion based on water uptake is applied to a spherical shaped vesicle. Results show a radius increase up to 20% in a time interval of the order of 10 minutes. On the other hand, we evaluate a model for membrane-cortex adhesion, which is related to membrane deformations due to local detachments. Simulations of the model are done considering both deterministic and stochastic dynamics. Results show that below a pressure difference threshold, only in stochastic simulations a membrane-cortex detachment occurs. Typical times for this process are of the order of 0.1 to 1000 s depending on the detachment condition imposed

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2016, Tutora: Marta Ibañes Miguez

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MAYORDOMO CORREAS, Oscar. Dynamics of vesicle and cell membranes driven by pressure differences. [consulted: 8 of August of 2026]. Available at: https://hdl.handle.net/2445/117591

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