Carregant...
Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Llicència de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/214503
Bioactive peptides and other immunomodulators of mushroom origin
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
For centuries, humans have used mushrooms as both food and pro-health supplements. Mushrooms, especially those related to the functions of the human immune system, are rich in dietary fiber, minerals, essential amino acids, and various bioactive compounds and have significant health-promoting properties. Immunoregulatory compounds in mushrooms include lectins, terpenes, terpenoids, polysaccharides, and fungal immunomodulatory proteins (FIPs). The distribution of these compounds varies from one species of mushroom to another, and their immunomodulatory activities depend on the core structures and chemical modifications in the composition of the fractions. In this review, we describe active compounds from medical mushrooms. We summarize potential mechanisms for their in vitro and in vivo activities and detail approaches used in developing and applying bioactive compounds from mushrooms. Finally, we discuss applications of fungal peptides and highlight areas that require improvement before the widespread use of those compounds as therapeutic agents and explore the status of clinical studies on the immunomodulatory activities of mushrooms and their products, as well as the prospect of clinical application of AMPs as ‘drug-like’ compounds with great potential for treatment of non-healing chronic wounds and multiresistant infections.
Matèries
Matèries (anglès)
Citació
Citació
DRZEWIECKA, Beata, WESSELY‐SZPONDER, Joanna, ŚWIECA, Michał, ESPINAL, Paula, FUSTÉ I DOMÍNGUEZ, Ester, FERNÁNDEZ‐DE LA CRUZ, Eric. Bioactive peptides and other immunomodulators of mushroom origin. _Biomedicines_. 2024. Vol. 12, núm. 7. [consulta: 8 de gener de 2026]. ISSN: 2227-9059. [Disponible a: https://hdl.handle.net/2445/214503]