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2014-01-31

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/110362

Characterization of CTX-M-14 and CTX-M-15 producing Escherichia coli strains causing neonatal sepsis

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Abstract

Neonatal sepsis is a disease affecting newborns ≤1 month of age with clinical symptoms and positive blood cultures. The number of Escherichia coli strains causing neonatal sepsis resistant to the antibiotics used in the treatment is increasing. In this study, two E. coli strains causing sepsis in neonates of mothers infected with an E. coli strain harboring extended spectrum beta-lactamases were characterized. The blaCTX-M-15 and the blaCTX-M-14 genes were found in an IncFIA and nontypeable transferable plasmids, respectively. In addition, these highly virulent strains belonged to ST705 and ST156 clonal groups, respectively. The presence of strains, which are highly virulent and resistant to ampicillin, gentamicin, and cephalosporins, makes a change in empirical treatment necessary as well as an increase in the surveillance of these infections.

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https://doi.org/10.1089/mdr.2013.0190.

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Infeccions per escheríchia coli, Septicèmia, Neonatologia, Plasmidis, Resistència als medicaments, Morbiditat

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Escherichia coli infections, Septicemia, Neonatology, Plasmids, Drug resistance, Morbidity

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SÁEZ-LÓPEZ, Emma, et al. Characterization of CTX-M-14 and CTX-M-15 producing Escherichia coli strains causing neonatal sepsis. Microbial Drug Resistance. 2014. Vol. 20, num. 4, pags. 281-284. ISSN 1076-6294. [consulted: 7 of October of 2026]. Available at: https://hdl.handle.net/2445/110362

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