Neonatal sepsis by bacteria: a big problema for children.

Abstract

Neonatal sepsis is an important but underestimated problem around the world. It is defined as disease affecting newborns ≤ 1 month of age with clinical symptoms and positive blood cultures. Infection is an important cause of morbidity and mortality during the neonatal period, despite the great improvements in intensive neonatal care and the use of extended spectrum antimicrobial agents. The incidence of this disease in developed countries is 1/1,000 in normal term neonates and 4/1,000 in preterm neonates. These values increase in low-weight preterm neonates. In developing countries, this incidence increases to 2.2-8.6/1,000 live births. Neonatal sepsis can be subdivided into early-onset neonatal sepsis and late-onset neonatal sepsis.