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Title: Enantioselective formal synthesis of (+)-madangamine A
Author: Are, Celeste
Pérez Bosch, Maria
Bosch Cartes, Joan
Amat Tusón, Mercedes
Keywords: Alcaloides
Compostos heterocíclics
Síntesi orgànica
Heterocyclic compounds
Organic synthesis
Issue Date: 27-May-2019
Publisher: Royal Society of Chemistry
Abstract: An enantioselective formal synthesis of the marine alkaloid madangamine A using phenylglycinol-derived lactam 1 as the starting enantiomeric scaffold is reported. The synthesis involves the construction of the C-9 substituted diazatricyclic ABC core and the final closure of D and E rings from the polyunsaturated skipped intermediate 19.
Note: Versió postprint del document publicat a:
It is part of: Chemical Communications, 2019
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ISSN: 1359-7345
Appears in Collections:Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

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