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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/150979
Oleocantal del Aceite de Oliva Virgen Extra y sus efectos en procesos neurodegenerativos
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[spa] El envejecimiento progresivo de la población mundial se asocia con un aumento en la incidencia de patologías relacionadas con la edad, como procesos inflamatorios y neurodegenerativos, de los cuales la demencia como enfermedad de Alzheimer (EA) tiene mayor prevalencia. El estilo de vida y los hábitos dietéticos se consideran factores de riesgo que condicionan su aparición. Existe evidencias de que la adherencia a la dieta mediterránea (DM) reduciría la incidencia de las patologías cognitivas relacionadas con el envejecimiento. En particular, se ha destacado que la ingesta de aceite de oliva virgen extra (AOVE) y su contenido en polifenoles serían responsables de dichos efectos beneficiosos. De estos compuestos, la investigación actual sugiere que el Oleocantal (OC) sería efectivo frente a la neurodegeneración, y especialmente la EA. Aunque parte de su actividad biológica y de los mecanismos de acción implicados están aún por determinar, se considera que su efecto neuro-protector se debería a su potente capacidad antiinflamatoria. Dentro del marco de DM y el consumo de AOVE, el OC ayudaría a prevenir la neuro-degeneración, mejorar sus síntomas y frenar su progresión. En el presente trabajo de revisión bibliográfica se examina la evidencia científica actualizada que respaldaría dicha hipótesis.
[eng] The progressive aging of the world population is associated with an increase in the incidence of age-related pathologies, such as inflammatory and neurodegenerative processes, of which dementia as Alzheimer's disease (AD) has a higher prevalence. Lifestyle and dietary habits are considered risk factors that condition their appearance. There is evidence that adherence to the Mediterranean diet (DM) would reduce the incidence of cognitive pathologies related to aging. Specially, it has been noted that the intake of extra virgin olive oil (EVOO) and its content in specific polyphenols, are responsible for such beneficial effects. Of these compounds, current research specifically that Oleocantal (OC) would be effective against neurodegeneration, and especially AD. Although part of its biological activity and the mechanisms of action involved are still to be determined, its neuro-protective effects will be due on its anti-inflammatory power. Within the framework of DM and the consumption of EVOO, OC will help to prevent neurodegeneration, improve its symptoms and slow its progression. In the present work of literature research, the updated scientific evidence that would support this hypothesis will be examined.
[eng] The progressive aging of the world population is associated with an increase in the incidence of age-related pathologies, such as inflammatory and neurodegenerative processes, of which dementia as Alzheimer's disease (AD) has a higher prevalence. Lifestyle and dietary habits are considered risk factors that condition their appearance. There is evidence that adherence to the Mediterranean diet (DM) would reduce the incidence of cognitive pathologies related to aging. Specially, it has been noted that the intake of extra virgin olive oil (EVOO) and its content in specific polyphenols, are responsible for such beneficial effects. Of these compounds, current research specifically that Oleocantal (OC) would be effective against neurodegeneration, and especially AD. Although part of its biological activity and the mechanisms of action involved are still to be determined, its neuro-protective effects will be due on its anti-inflammatory power. Within the framework of DM and the consumption of EVOO, OC will help to prevent neurodegeneration, improve its symptoms and slow its progression. In the present work of literature research, the updated scientific evidence that would support this hypothesis will be examined.
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Treballs Finals de Grau de Nutrició Humana i Dietètica, Facultat de Farmàcia i Ciències de l'Alimentació, Campus de l'Alimentació de Torribera, Universitat de Barcelona. Curs: 2019-2020. Tutor: Francisco Javier Luque Garriga
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GONZÁLEZ PÉREZ, Paula inocencia. Oleocantal del Aceite de Oliva Virgen Extra y sus efectos en procesos neurodegenerativos. [consulta: 29 de desembre de 2025]. [Disponible a: https://hdl.handle.net/2445/150979]