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http://hdl.handle.net/2445/157699| Title: | PPARβ/δ: A Key Therapeutic Target in Metabolic Disorders |
| Author: | Palomer Tarridas, Francesc Xavier Barroso Fernández, Emma Pizarro Delgado, Javier Peña, Lucía Botteri, Gaia Zarei, Mohammad Aguilar, David Montori Grau, Marta Vázquez Carrera, Manuel |
| Keywords: | Homeòstasi Obesitat Diabetis Metabolisme cel·lular Farmacologia Homeostasis Obesity Diabetes Cell metabolism Pharmacology |
| Issue Date: | 20-Mar-2018 |
| Publisher: | MDPI |
| Abstract: | Research in recent years on peroxisome proliferator-activated receptor (PPAR)β/δ indicates that it plays a key role in the maintenance of energy homeostasis, both at the cellular level and within the organism as a whole. PPARβ/δ activation might help prevent the development of metabolic disorders, including obesity, dyslipidaemia, type 2 diabetes mellitus and non-alcoholic fatty liver disease. This review highlights research findings on the PPARβ/δ regulation of energy metabolism and the development of diseases related to altered cellular and body metabolism. It also describes the potential of the pharmacological activation of PPARβ/δ as a treatment for human metabolic disorders |
| Note: | Reproducció del document publicat a: https://doi.org/10.3390/ijms19030913 |
| It is part of: | International Journal of Molecular Sciences, 2018, vol. 19, num. 3, p. 913 |
| URI: | http://hdl.handle.net/2445/157699 |
| Related resource: | https://doi.org/10.3390/ijms19030913 |
| ISSN: | 1661-6596 |
| Appears in Collections: | Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica) |
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| File | Description | Size | Format | |
|---|---|---|---|---|
| 680789.pdf | 1.34 MB | Adobe PDF | View/Open |
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